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التصفح حسب تاريخ النشر
التصفح حسب مكان النشر
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تم العثور علي : 10
 تم العثور علي : 10
  
 
إعادة البحث

Thesis 2022.
Ahmed Mohamed Mortada Mohamed,
617 الجراحة والموضوعات ذات الصلة  
Cardiac surgery
تصفح الوعاء  

Thesis 2020.
Zahran, Mohamed Magdy Kandi,
572 الكيمياء الحيوية  
The present thesis aims at finding out the most
appropriate conditions to oxidize the common
polysaccharide maize starch using the powerful sodium
perborate/aminoiminomethanesulfinic acid (SPB/AIMSA)
redox system - keeping in mind the quality of the oxidized
starch - the cost of the oxidizing process and its
environmental impact.
Structural changes in the starch molecules brought
about by oxidation were appraised in terms of the carbonyl
and carboxyl groups as well as the apparent viscosity. It was
found that starch undergoes oxidative degradation using the
said redox system. This was demonstrated by a significant
enhancement of the carbonyl and carboxyl groups along
with a significant decrease in the apparent viscosity as
compared with the unoxidized starch. Application of the
oxidized starch - prepared under the optimum oxidation
conditions - to cotton fabric was also carried out to evaluate
the suitability of such modified starch as sizing agents.
Results of tensile strength (TS) and elongation-at-break
(EAB) measurements of the fabric samples as well as the
Thesis Abstract
xviii
easiness of size removal from these samples compared with
those sized with the unoxidized starch signify that the
oxidized starches are more satisfactory sizing agents.
Key words: Maize starch - oxidation - sodium perborate -
aminoiminomethanesulfinic acid - sizeability - Microbial polysaccharides
تصفح الوعاء  

Thesis 2017.
Awad, Basma Mosilhy Kassem.
615 علم الصيدلة والعلاج  
pharmacy - Abstract:
Historically - plants have been used since ancient times and in folklore for the treatment of many diseases and illnesses including chronic diseases and cancer care. In recent years - plants have been getting more attention as drugs worldwide.
Achillea fragrantissima (Forssk.) Sch. Bip. is a desert plant which belongs to Asteraceae family and is known as Qaysūm in Arabic. We selected it as a member of family Asteraceae to be the plant under investigation. It grows in Sinai - Egypt and is used in folk medicine by Bedouins for treatment of many diseases. In addition it has been tested for its anticancer activity. The broad aim of this thesis was to conduct a phytochemical investigation and biological confirmation of the plant Achillea fragrantissima (Forssk.) Sch. Bip. and its constituents as an anticancer agents illustrating their mechanism of action.
The initial part of this work focused on large scale extraction of the plant with different solvents - bioactivity-guided fractionation led to the isolation of seven compounds followed by determination of the chemical nature of them. The isolated compounds are:
The known compounds Eupatilin 7- methyl ether (3) - chrysosplenol D (4) - Cirsiliol (5) - β-Sitosterol-3-O-β-D-glucoside (6) and Cirsimaritin (7) while Piceol (1) and Veratric acid (2) are reported here for the first time from Achillea fragrantissima (Forssk.) Sch. Bip.
The second part of this work focused on evaluation of the in-vitro cytotoxic activity of the methanolic extract of A. fragrantissima (Forssk.) Sch. Bip - its fractions and the isolated compounds 1 - 2 - 3 - 4 - 5 and 7 against different cell lines using the Sulpho-Rhodamine-B (SRB) assay. The extract - fractions (4 - 5) and the compounds 3 - 4 - 5 and 7 showed high cytotoxic activities when compared to appropriate reference drug (doxorubicin) and IC50 values (the concentrations of drug required to produce 50% inhibition of cell growth) were calculated for the isolated compounds.
The third part of this work focused on evaluation of the in-vivo antitumor activity of the methanolic extract of A. fragrantissima (Forssk.) Sch. Bip. and its isolated compounds 3 - 4 - 5 and 7 using Ehrlich’s Ascites Carcinoma (EAC) model in mice. A. fragrantissima (Forssk.) Sch. Bip. extract and its isolated compounds reduced the tumor weight compared to EAC-Control group. In addition - the compounds 3 - 7 treatments produced a dose dependent reduction in tumor weight. Determination of serum tumor necrosis factor – alpha (TNF-α) level highlighted that A. fragrantissima (Forssk.) Sch. Bip. extract and its isolated compounds significantly reduced its serum level compared to the EAC-Control group - where 3 - 5 - 7 groups produced a significant reduction in serum level of TNF-α compared to all other groups. Furthermore - A. fragrantissima (Forssk.) Sch. Bip. extract and the isolated compounds significantly increased the total antioxidant capacity (TAC) compared to EAC-Control especially compound 7. The histopathological examination revealed that A. fragrantissima (Forssk.) Sch. Bip. extract and its isolated compounds produced a better differentiation of tumor cells - with reduced nuclear pleomorphism and better formed tubular structures especially with high dose indicating the induction of apoptotic mechanism.
Finally - an in silico study was performed as a step to elucidate the mechanism of the cytotoxic effect of the compounds isolated from A. fragrantissima (Forssk.) Sch. Bip - where the structure of cirsiliol (5) was docked into the active sites of the crystal structures of PI3K and Akt - two protein kinases that are significantly involved in prostate and breast cancer processes.
Key Words: Achillea fragrantissima (Forssk.) Sch. Bip - anticancer - Ehrlich’s Ascites Carcinoma - Docking.
Aim of work:
Flora of Egypt especially in Sinai Peninsula is rich and diverse with medicinal and aromatic plants as well as herbs and spices. These plants have been used by local people in folk medicine for curing human and animal illnesses. The plants of genus Achillea as a part of Sinai Peninsula flora were and still a rich source of valuable natural products for treatment of many diseases; therefore - this study was designed to fulfill:
1. Collection of the plant material from Sinai Peninsula in Egypt.
2. Bioactivity-guided fractionation to isolate active compounds using different chromatographic techniques.
3. Identification and structure elucidation of the isolated compounds - using 1D NMR - 2D NMR and DEPT measurements.
4. In vitro cytotoxic and in vivo antitumor evaluations of the methanolic extract of Achillea fragrantissima (Forssk.) Sch. Bip. and its isolated compounds.
pharmacognosy
تصفح الوعاء  

Thesis 2017.
Hamed, Ahmed Magdy Mohamed.
617 الجراحة والموضوعات ذات الصلة  
412 علم الاشتقاق  
Cardiothoracic Surgery.All patients in this study were subjected to the following:
1- Preoperative and postoperative ECG.
2- Preoperative and postoperative echocardiography.
3- Laboratory investigations:
 Routine investigations.
 Estimation of creatinine.
 Estimation of serum level of LDH - Troponin and CK-MB.
 Estimation of serum level of NT-proBNP preoperative
and 24 hours after the operation.
- NT-Pro BNP was analyzed using a commercial NT-pro BNP
ELISA Kit (Biomedica - Vienna - Austria).
4- Cardiopulmonary bypass time.
5- Aortic cross clamping time.
6- Requirement for cardiac support immediately after the operation
( drugs or intra-aortic balloon )
7- Duration of ventilation dependence
8- Duration of ICU and hospital stay.
9- Postoperative complications: (neurological- renal-pulmonarybleeding-
wound infection)
10- Operative mortality: includes in hospital death as well as death
within 30 days after surgery.The results of the present study:
-We found that there was significant relationship between NTproBNP
and need of inotropes after surgery.
-Also - our results showed that there was statistically significant
difference between pre and postoperative NT-proBNP level.
Furthermore - there was significant difference between preoperative
and postoperative LDH and CK-MB.
-In this study - there was significant relationship between NT-proBNP
and duration of ventilation dependence.
-We also found significant relationship between NT-proBNP with
CBP time and aortic cross clamp time.
-As regards outcome - there was significant relationship between NTproBNP
with prolonged ICU stay and hospitalization also - there was
significant relationship between NT-proBNP and appearance of most
postoperative complications - Cardiothoracic Surgery
تصفح الوعاء  

Articles
Abd El -hameid, A .M.
615 علم الصيدلة والعلاج  
Vernalization - Globe artichoke - Artichoke
Annals of agricultural science, Moshtohor
Vol. 46, no. 4 (Des. 2008) /
   

Thesis 2010
SHAFIE,WAFAA WAHBA MOHAMED
633 المحاصيل الحقلية والنباتية  
Wafaa Wahba Mohamed Shafie: Analysis of Gene Action for Yield and Quality characteristics in Diallel Crosses of Sesame. Unpublished Ph.D. Thesis - Department of Agronomy - Faculty of Agriculture - Ain Shams University - 2010. br Eight sesame genotypes were crossed in a diallel mating design - excluding reciprocals - to produce 28 F1 hybrid seeds in 2004 season and the 36 entries (8 parents + 28 F1’ s) were evaluated for eleven traits in 2005 season. The eight genotypes were re-crossed in the same diallel pattern in 2005 season and the 36 entries were evaluated for the same traits in 2006 season aiming to study heterosis - combing abilities - types of gene action and heritability - as well as correlation and path coefficient analysis for earliness - yield attributes and oil and protein contents in both seasons. br The results indicated that the mean squares due to all 36 genotypes as well as mean squares due to parents and crosses were highly significant for all studied characters - i.e - days to flowering - height of first capsule - plant height - fruiting zone length - number of fruiting branches/pant - number of capsules/plant - capsule length - 1000-seed weight - seed yield/plant - oil and protein percentages in both seasons - revealing the presence of sufficient genetic variability in the studied genotypes. br Parents vs. crosses mean squares as an indication to average heterosis for all hybrids were significant in all traits. Significant desirable negative or positive heteosis relative to mid and better parents were observed in many crosses for all traits in both seasons. br Both general and specific combining ability mean squares were found to be highly significant for all studied traits in both seasons - indicating the importance of both additive and non-additive gene effects in the expression of the studied traits. The ratios of GCA/SCA variances were greater than unity for days to flowering in the first season and near unity in the 2nd - height of first capsule - plant height - fruiting zone length - no. of fruiting branches - no. of capsules/plant - capsule length - 1000-seed weight - seed yield/plant - oil % and protein % in both seasons - indicating that the inheritance of these traits were mainly controlled by additive gene effects. However - ratios were less than unity for no. of capsules/plant in both seasons illustrating that this traits was mainly controlled by the non-additive gene effects. Good general combiner parents were identified for each of the studied traits. Some crosses exhibited significant desirable SCA effects in all studied traits and some of them involved at least one good general combiner parent - therefore - considered as promising F1 cross combinations for improving sesame traits. br High estimates of heritability values in the narrow sense exceeding 50% were detected for plant height - number of branches/plant - fruiting zone length - oil% and protein% in the two seasons. These values ranged -#102;-#114;-#111;-#109; 50.04% for number of branches/plant in 2005 season to 66.04% for oil % in 2006 season - indicating the importance of additive and additive x additive gene effects in the inheritance of these traits and consequently the effectiveness of selection for improving such traits in early segregating generations. However - moderate values of heritability in the narrow sense were obtained in both seasons for number of capsules/plant - capsule length - 1000-seed weight and seed yield/plant - ranging -#102;-#114;-#111;-#109; 32.67% for 1000-seed weight in the 1st season to 45.63% for seed yield/plant in the 2nd. With regard to the two earliness traits - i.e. days to flowering and height of first capsule - low estimates of narrow sense heritability were obtained in both seasons ranging -#102;-#114;-#111;-#109; 21.24% for days to flowering in the 2nd season to 27.49% for height of first capsule in the 2nd season - indicating that - in the case of moderate and low heritabilities in the narrow sense - response to selection for these traits in later segregating generations would be expected. br Except for oil% - the other 10 earliness - yield attributes and protein content exhibited consistent high estimates of broad sense heritabilities as compared to their respective narrow sense values ranging -#102;-#114;-#111;-#109; 84.6% for 1000-seed weight in 2005 season to 99.4% for height of first capsule in both seasons - indicating that dominance effects had prominent role in the inheritance of these traits. br Path analysis indicated that - plant height - fruiting zone length - height of first capsule and no. of capsules/plant and their interactions a crosse as the main sources of seed yield variation br . br Key Words: Sesame - Diallel crosses - Combining abilities - Heritability - Earliness - Yield - Oil - Protein - Correlation and path analysis. br Heterosis estimates - Wafaa Wahba Mohamed Shafie: Analysis of Gene Action for Yield and Quality Characteristics in Diallel Crosses of Sesame. Unpublished Ph.D. Thesis - Department of Agronomy - Faculty of Agriculture - Ain Shams University - 2010.
Eight sesame genotypes were crossed in a diallel mating design - excluding reciprocals - to produce 28 F1 hybrid seeds in 2004 season and the 36 entries (8 parents + 28 F1’ s) were evaluated for eleven traits in 2005 season. The eight genotypes were re-crossed in the same diallel pattern in 2005 season and the 36 entries were evaluated for the same traits in 2006 season aiming to study heterosis - combing abilities - types of gene action and heritability - as well as correlation and path coefficient analysis for earliness - yield attributes and oil and protein contents in both seasons.
The results indicated that the mean squares due to all 36 genotypes as well as mean squares due to parents and crosses were highly significant for all studied characters - i.e - days to flowering - height of first capsule - plant height - fruiting zone length - number of fruiting branches/pant - number of capsules/plant - capsule length - 1000-seed weight - seed yield/plant - oil and protein percentages in both seasons - revealing the presence of sufficient genetic variability in the studied genotypes.
Parents vs. crosses mean squares as an indication to average heterosis for all hybrids were significant in all traits. Significant desirable negative or positive heteosis relative to mid and better parents were observed in many crosses for all traits in both seasons.
Both general and specific combining ability mean squares were found to be highly significant for all studied traits in both seasons - indicating the importance of both additive and non-additive gene effects in the expression of the studied traits. The ratios of GCA/SCA variances were greater than unity for days to flowering in the first season and near unity in the 2nd - height of first capsule - plant height - fruiting zone length - no. of fruiting branches - no. of capsules/plant - capsule length - 1000-seed weight - seed yield/plant - oil % and protein % in both seasons - indicating that the inheritance of these traits were mainly controlled by additive gene effects. However - ratios were less than unity for no. of capsules/plant in both seasons illustrating that this traits was mainly controlled by the non-additive gene effects. Good general combiner parents were identified for each of the studied traits. Some crosses exhibited significant desirable SCA effects in all studied traits and some of them involved at least one good general combiner parent - therefore - considered as promising F1 cross combinations for improving sesame traits.
High estimates of heritability values in the narrow sense exceeding 50% were detected for plant height - number of branches/plant - fruiting zone length - oil% and protein% in the two seasons. These values ranged from 50.04% for number of branches/plant in 2005 season to 66.04% for oil % in 2006 season - indicating the importance of additive and additive x additive gene effects in the inheritance of these traits and consequently the effectiveness of selection for improving such traits in early segregating generations. However - moderate values of heritability in the narrow sense were obtained in both seasons for number of capsules/plant - capsule length - 1000-seed weight and seed yield/plant - ranging from 32.67% for 1000-seed weight in the 1st season to 45.63% for seed yield/plant in the 2nd. With regard to the two earliness traits - i.e. days to flowering and height of first capsule - low estimates of narrow sense heritability were obtained in both seasons ranging from 21.24% for days to flowering in the 2nd season to 27.49% for height of first capsule in the 2nd season - indicating that - in the case of moderate and low heritabilities in the narrow sense - response to selection for these traits in later segregating generations would be expected.
Except for oil% - the other 10 earliness - yield attributes and protein content exhibited consistent high estimates of broad sense heritabilities as compared to their respective narrow sense values ranging from 84.6% for 1000-seed weight in 2005 season to 99.4% for height of first capsule in both seasons - indicating that dominance effects had prominent role in the inheritance of these traits.
Path analysis indicated that - plant height - fruiting zone length - height of first capsule and no. of capsules/plant and their interactions a crosse as the main sources of seed yield variation
.
Key Words: Sesame - Diallel crosses - Combining abilities - Heritability - Earliness - Yield - Oil - Protein - Correlation and path analysis.
Heterosis estimates
تصفح الوعاء  

Thesis 2010 .
Mahmoud El Sayed Roushdy,Tamer
616 الأمراض  
Diagnosing and treating metabolic syndrome
different components as well as its
medical/physical complications
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Thesis 2011 .
Kamal ElDin Shawky Ismail,Mona
612 الفسيولوجيا البشرية  
Plasma levels of total proteins - albumin - alanine transferase (ALT) - aspartate transferase (AST) - and lactate dehydrogenase (LDH) - as well as - blood levels of reduced glutathione (GSH) and hepatic levels of GSH and malondialdehyde (MDA) - in thymoquinone-D-galactosamine-treated group
Mona Kamal ElDin Shawky Ismail،
تصفح الوعاء  

Book 2006
Hoelsher,David S.
ISBN: 1589065034
This paper describes recently established deposit insurance systems - identifying emerging trends. In line with previous IMF work on the subject - it argues against the development of ”best practices” applicable to all systems. Rather - it stresses the importance of incorporating each country’s individual objectives in adopting a deposit insurance system - as well as that country’s characteristics - to ensure an effective system that minimizes disincentives and distortions to financial sector intermediation. The paper includes a summary of the academic literature
international monetary fund.

Thesis 2003
Mona Magdy Halim Eskender
616 الأمراض  
” The present study is a retrospective study done on 326 patients of prostate cancer in Mansoura University Hospital and Urology and Nephrology center during the period between January 1990 to January 2000.
” Our study revealed that prostate cancer was common among patients over the age of 65 years (50.9%) and in those with no family history. Smokers represented 35.3% of our patients. The commonest presenting symptom in our patients was urine retention (89.6%) - to less extent bony aches and dysuria (59.2% for each) - while hematuria and frequency were less common presenting complaints.
” Among 326 patients included in our study - only 226 patients received treatment and had adequate follow-up data. Thirty patients received radical prostatectomy - 22 patients received radical radiotherapy with hormonal cytoreduction - 156 patients received hormonal treatment (subcapsular orchidectomy and/or antiandrogen therapy) and 18 patients received other treatments.
” Using multivariate analysis of different predictors of response rate in patients with prostate cancer - it was found that lines of treatment were the most statistically significant predictor of response rate followed by pathological type then clinical stage at time of presentation - while the most significant predictors of overall survival rate were lines of treatment and pathology - followed by clinical stage. However - lines of treatment - pathology and clinical stage had equal statistical significance in predicting progression free survival rate in patients with prostate cancer.
” Health education programs about risk factors of prostate cancer - screening techniques as well as effective therapeutic modalities are recommended
MANSOURA UNIVERSITY

 







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