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Abstract Stem cells are characterized by two features: first, the ability to self renewal and, second , they must have the capacity to differentiate into many cell lines (multilineage differentiation), range from the totipotency, to the pluripotency, multipotentiality, and lastly to the unipotentiality. Haematopoietic stem cell transplantation has been rabidly increased and substantially changed over the last decades. Allogeneic transplants are haematopoietic stem cells from a healthy donor. Auotologous transplants are stem cells from the patient’s own bone marrow or peripheral blood. The number of haematopoietic stem cells in blood can be deliberately expanded. These expansions often referred to as mobilization. Mobilization may be achieved using cytotoxic chemotherapy, haematopoietic growth factor or a combination of two. |