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Abstract
Cirrhosis has been known to be associated with a hyperdynamic circulation for the past 50 years, manifesting primarily as increased cardiac output and decreased systematic vascular resistance.
Suboptimal cardiac response following exercise in both alcoholic and non-alcoholic cirrhotic patients compared with controls has previously been reported.
The phenomenon of baseline hypercontractility, but depressed contractile response to physical stimuli, is now termed cirrhotic cardiomyopathy.
The aim of the present study:
to assess the presence of haemodynamic, cardiac structural and functional changes in cirrhotic patients and detection of possible changes that may occur as a response to exercise.
Our study included three groups of patients:
* Group I:
includes 10 healthy non smoking individuals, age, sex and body mass index (BMI) matching with other groups (serving as control group).
* Group II:
Cirrhotic non ascetic group; including 20 patients
* Group III:
Cirrhotic ascetic group; including 20 patients.