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Abstract A t _Bri.o.~cr.hemical deter~mi~atiott_s:The mean velu6 ± SE for the seru’i1concentration of each of totel protein, albumin, glo~ulin are presented in table 2. The last coulmn of the table represents the ut” velue obtained from the comparison of the mean ve.Lue of the two groups using umpaired tiT”test of significance. The serum level of each • of tote.lprotein and albumin of the vf.r-aL hepatitis ~.oup was lower than that of the control grOtl]?_ However, the difference between the t1ro mean values was significant only for albumih (p ~Ol)~ • Globulin, on the other hand, had the B~me concent ration in the two gro upa, 2. i___erur’ m__ Br..•i_• l•.••i•~r~_ub••i••~n ( Tote•• l and direct _) The mean valile± SE for each of serum totsl and direct bilirubin for both the control end viral hepatitis grollp are presented in te1:>le~. The serum level of each of botrxL and direct bilirllbin ”1E!.S z-emr-r-kab Ly .\ligherin the viral hepatitis than the control grollp. The magnd t ude of increese was ).475 fig% ( 695 % ) and ).190 fig% ( 159 % )for the total and direct bilirubin, respectively. Urrprd.r-ed ”T” test of significance showed that the difference bet’~en the tvrogrollps in e2ch peremeter is statistically TABLE (4) • Hean Values and standard errors of serum Levels of total protein • albumin • g10bulin and Creatinine in control and Viral hepatitis graups. Parameter Control group ( Ne 23 ) Viral hepatitis group (r’e20) ,,~” value Total protein • g % 7.2~ 0.15 6.98 ! 0.19 1.093Aibumin • g )(, l:.84;!: 0,16 3.99! 0.15 3.909 Globulin , g (,t, 2.99;!:o.ri 2.99; 0.20 0.000 Crea.tinine • mg If, 0.911!0.04 1.06+ 0.06 1.818 ** » L: .01 TABLE (J). Mean values and standard errors of serum levels of total and direct bilirubin in control and viral hepatitis groups. Control group (N:=23) Viral hepatitis ”t” group (N=2G) p Direct bilirubin.ng~ 0.2CtO.045 signifieent ( p <.01 ), table 3. The serum creatinine concentration fOr the control and viral ~epatitis groups is nresented in table Z as x :!:. SE. The difference between tl-Je t”IO grouPR ”’I’lli’! statisticnlly insignificnnt.T..t_.S’GPT~.and._aa~l~ali..n~.e•__ The mor-nvr.Lue + SE for the Rerum 10’11’)1of 08C11. of SGOT,SGPTarid r.Lkr.Lfne n1J.osnh8t8s8 n:r-enresenttod in noted in the vLr-r.Lhenpti tis gJ”OllT8JS cOl11n’”1retdo the normrL cont r-oL ,’!roup. For e[1c1:1enz’>’111thOe oi·8ference bet’.7oen t.1-:1emern voLues of the tyro r~rO!lns”’8R 8trtidicoll” si”ulific”nt ( P i( .(’1 ). B. H--o_r-•m...•_on-a-_l, ._-P-E-7_S8,’t.r.•_-: The moon vo.Lue + SE for 02C’1 of sera”, t”t”l th”,:ro:d.ne ratio for hot’) the control 8’1d virpl”en,-,ti tis gronD nrc presented in tnhIe 5 and p’rfl’1h.ic,-111,i11ust-r”ted in figures I and 2. Unnrd.r-od ”Til test ’’’’’’1’’ ’”1.’1nlied to the dCl-tr to test tbe sig’1.ific~moe of il:i.ffe-ren~e be tween the t’.eromoon vrLue s of er.ch nnr8meter and the r-esu l t s of” 8:1Chf’l1rli”sis nre ShOFn1in the IrEt cou’lumn of the t”bl0 ”’8 ”Til vr Lucs ; - 70 - T~BLE (~) Mean values and standard errors of s~rum levels of SGOT, SGPT and alkaline phosph~tase in control and viral hepatitis groups. Para’ilenter Control group (N - 23) Viral hepatitis ”t” group value (N - 20) soor , wrobleT”J’skiunits 10.151:0.46 SGPI’, wroblewski units lO.65:t0•69 137.50+20.60 6.459** Alkaline phospha- 10.(4+0.80 tase, kind and king units ** P £. .01 -------------~-- ---- --- - 71 - THBJ”E(5.);’leanva1ues and standord errors 0:1: Serum total thyroxine and normalized th~~ine ratio in control and virll hepatitis groups. Control ., Virll hepatitis ,.,t,,. Parameter group group value ( iv •• 23 ) ( N •• 20 ) Total thyroxine J 10. 40 + 0.86 NTH 1.020.- 0.012 1.978 <r t: .01 72 TOTAL THYROXINE N (J) co o •1...1..• ( Q --” :t> (j) Z rTJ :.:0 0 .c;z i- I<....-. ---1 I :xl 0 J> -j I r J> r ! I Ii rTl ---1 \J T J> -c •-..-...I• JJ ---1 0_. X•.....• (J) -7 .”- rTi CI ::0 •.....• Z 0~ -L0. n0 (J) _., L_ ---1 :JJ 0r .=~~--m~l •.m.•.m:m~~:!,•;!•:!!!!:!!·!!!!.!~!!!!!!!!!!!!’l1r!!:r:!!’!re:!’!!!!~rnm:~ ••r..r•.•.~~.r..r..~.J iii::::: :~::~::::: :::::::::ii :::::: i::Uli::: :::::~:~: :~::::1~:: ·•:••.·•·•.·:.·.·:::5::::55 I::::::::: •••••••••••••••• ••••u ••~.... ·.·.·.Iiiiiiiilf---l ::~::::: :u::••:•:•::~:••:.= II:::::::::::::::::::: :::~:::::::: •••...••• :~::~:::::::::::I::::::~::::::::::::::::::::::::::II:~:::::::::::::::: II:::::::::::::::::: :::::::: :::55::::: I:::::::I:::::::: I::::::::: .< I -> N noZ -I ::0 or - 75 - errors for t’l€ two groups were very close. The coefficients of vrcrie:rlce for the -:’<TRwere 5.64 and 6.38 % for t:’le control and viral ’1.epetitis groups, respectively. --”---- --”--- - 76 - c. The relationship between each parameter of blood analysis and thyroid function parameters in viral hep8titis pa.tients. The relationship between each of serLUIItotF’l protein, albumin, globUlin, SGOT& SGPTand each of T4 and JTTR was tested by Peor-son nroduct moment correlstiO! l eoefficient • Sa!i’Jl1?rVof this nnal \Tsis is nresented in table 6. The only significpnt 0ifference obtained ”ms between SG,)Tand tot?l T4 (p <.(5). This significpnt COrre Lrt Lon was nosi ti ve indic ~ting thpt with the increase in serum level of SGOT, there was a cC’rres))ondin::c increpse in T4. The 1Jrediction eqLll”tion for such a relptionship was found to he: y = 7.80,0 + 0.016 x (Serlrn thyroxine) (SGOT) It should be noted thpt there ”’?S [) tendency for positive cor)~elptions ’)etween SGO’” & 1’TR. and SGPT & T4, I’llthOUgh the obt eLned ”r”s did not r-e ach t’le statistical significaIlce. -77- Table (6). Correlntion Coefficient (r) between blood c,;lnlysis p2,rometers and thyroid function pnrnneters indices in vir2~ hepntitis UrI!Vnlue DnrC::lster T4 J’’TR Totnl protein - 0.190 - 0.08) Albunin - 0.023 - 0.060 Globulin - 0.196 - 0.0)6 SGOT 0.468 )( 0.)42 SGPT 0.415 0.011 |