الفهرس 
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Abstract
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SUMMARY AND CONCLUSIONS
Preeclampsia is one of the major problems in obstetric.
Many theories and etiological factors had been studied to
elucidate the cause of preeclampsia.
Recently evidence suggested that a circulating digoxin
like immunoreactive substance DLIS may be an important
factor in the pathophysiology of preeclampsia.
Our study included 62 primigravidae, from the same
socio-economic class, from 16 to 39 years old. Who were
admitted in labour, primigravidae were subdivided into 3
groups :
1. Group I (Control group) it included 30 normotensive
primigravidae.
2. Group II (Mild-preeclamptic group) it included 17
primigravidae with mild preeclampsia.
3. Group III (severe preeclamptic group) it included 15
primigravidae with severe preeclampsia.
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All women in the three groups were subjected:
1) To complete examination of the neonate (foetal birth
weight, Apgar score at 1 minute and 5 minutes and
gestational age).
2) Urine analysis for albumin.
3) Blood investigation sera collected from mothers and
the foetuses were tested for estimation of DLIS by an
Enzyme-Linked Immuno-Sorbant-Assay technique (ELISA) at
delivery.
Our study showed that :
1- There was a significant increase of the mean serum
concentration of maternal DLIS in cases with severe
preeclampsia, compared to normal and mild preeclamptic
groups.
2- A positive correlation was found between maternal DLIS
and gestational age in normal group, but not in both
preeclamptic groups.
3- Foetal concentration of DLIS did not differ
significantly between the three groups.
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4- Foetal DLIS was signHicantly higher than the
corresponding maternal concentration, in the three
groups.
5- A negative correlation was found between foetal DLIS
and infant birth weight.