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Abstract Aspirin (Acetyte salicylic acid) have analgesic, antipyretic, and anti-inflammatory effects. It is still the drug of choice in juvenile rheumatoid arthritis and so, treatment should be started with it. The aim of the present work was to study some ultrastructural changes in proximal and distal convoluted tubules of the kidney as a result of Aspirin adminstration. The present study was carried out on 44 adult male albino rats, weighting from 150-200 gm body weight. They were divided into four main groups: Group I: Formed of 10 rats being kept without any treatment and served as control for all experimental groups. Group 11: (sham control): Consisted of 10 rats were given distilled water (the dissolving vehicle for aspirin) using the same doses and periods as experimental group. Gourp 111: Included 18 rats that were further subdivided into three subgroups. |