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Abstract Aphaeresis is a medical procedure that involves removing whole blood from a donor or patient and separating the blood into individual components so that one particular component can be removed. The remaining blood components then are re-introduced back into the blood stream of the patient or donor. All aphaeresis procedures involve connecting the blood in the patient/donor’s veins through tubing to a machine that separates the blood components. The separation is done by either a centrifuge process or a filtration process on the blood in the machine. The entire procedure is painless and typically takes about two hours, or only slightly longer than a conventional blood donation. Aphaeresis is used for the collection of donor blood components as well as for the treatment of certain medical conditions in which a part of the blood that contains disease-provoking elements is removed. There are large categories of component collections: plasmapheresis, erythrocytapheresis, plateletapheresis, leukapheresis and stem cells harvesting. Therapeutic aphaeresis is classified into therapeutic depletion (RBCs, WBCs or platelets depletion) and therapeutic exchange (plasma exchange or RBCs exchange). Serious complications of donor aphaeresis are rare. Minor complications of donor aphaeresis can include bleeding at the donation site and feelings of light headedness that usually resolve quickly. |