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العنوان
Pharmacognostical study of arnebia hispidissima (Lehm) DC /
المؤلف
Abd Rabo, Eman Mohamed Abd El­-Karim.
هيئة الاعداد
باحث / ايمان محمد عبدالكريم
مشرف / حسن الراضى على سعد
مشرف / حسنى عبدالفتاح عبدالرحمن
مشرف / عطاالله فؤاد على أحمد
الموضوع
Pharmacognocy. Pharmacognosy - History.
تاريخ النشر
2005.
عدد الصفحات
323 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
العلوم الصيدلية
تاريخ الإجازة
01/01/2005
مكان الإجازة
جامعة المنصورة - كلية الصيدلة - Deptarment of pharmacognosy
الفهرس
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Abstract

1­Preliminary Phytochemical screening of roots of Arnebia hispidissima (Lehm.) DC., revealed the presence of unsaturated sterols and/or triterpenes, carbohydrates and/or glycosides, naphthoquinones, alkaloids and condensed tannins. 2­Phytochemical investigation of the petroleum ether extract, n­hexane, methylene chloride and ethyl acetate extracts lead to isolation of 9 compounds which characterized using various chromatographic and spectroscopic techniques. The isolated compounds are: ­ Arnebidin: is a new naphthoquinone dimer. It is reported here for the first time from a natural source, Arnebacene: is a new hexahydroanthracene derivative and it is reported here for the first time from a natural source, Arnebin­7: is a naphthoquinone compound and was previously identified. It is reported here for the first time from the Egyptian species, Tetracosanyl­4­hydroxy­3­methoxy­trans­cinnamate: is a phenyl propanoid ester isolated here for the first time from genus Arnebia Forssk, Vanillic acid: is an aromatic hydroxy acid and reported here for the first time from genus Arnebia Forssk, Mixture of esters of 2­ethyl­1­hexanol, as an aliphatic alcoholic moiety, and linoliec, oleic, lauric, linolenic, capric, myrestic, caprilic, caproic and other unidentified fatty acids, as acid moieties. Esters of this alcohol were isolated and reported here for the first time from the Boraginaceae, mixture of esters of an aliphatic alcohol which need further investigation to establish its structure, and palmitic, linoleic, oleic, lauric, capric and linolenic and other unidentified fatty acids, as acid moieties, a mixture of gb­ssitosterol and stigmasterol in a ratio of 7:3, a long chain aliphatic alcohol needs further investigation to determine its structure. 3­Macromorphological and Micromorphological studies of root, stem, leaf, inflorescence, flowers, fruits and seeds of Arnebia hispidissima (Lehm.) DC. revealed the identification of these organs and their powdered form.