الفهرس | Only 14 pages are availabe for public view |
Abstract Study Design:. Twenty five full term newborn infants (Gestational age: 38-42 weeks) born at Mansoura University Hospital and referred to the neonatology unit of Mansoura University Children’s Hospital within the first 24hour of life with the diagnosis of HIE were enrolled prospectively in the study. All infants were subjected to full history taking, complete general and neurological examinations. EEG and MRI were done. EEG was done within the first 72 hours of life. MRI was done between 1 and 4 weeks after birth. Results:. significant correlation between the severity of HIE and EEG background activities, and between EEG background activities and neurodevelopmental outcome all 12 months of life. Significant relation was found between MRI findings and HIE severity. good correlation between EEG and MRI findings. severity of HIE was correlated with neurodevelopmental outcome. Conclusion : Abnormalities in EEG background activity are particularly associated with poor neuro-developemntal outcome significant differences in the MRI findings in patients with different grades of HIE severity Abnormal MRI scans had a sensitivity of 100%, specificity of 42.8%, positive predictive value of 81.8% and a negative predictive value of 100% in predicting poor neurodevelopmental outcome. |