الفهرس 
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Abstract
Background: Hirsutism is the presence of excessive terminal hair in androgen-dependent areas in a female. The role of insulin resistance is well documented in cases of hirsutism associated with ovarian or adrenal hyperandrogenaemia. However the role of adiponectin as a marker of metabolic consequences in patients with hirsutism has not been conclusive.
Aim: To assess serum adiponectin level and insulin resistance in female patients with hirsutism to improve the management of this common dermatological complaint.
Subjects and methods: This case control study included 25 patients presenting with hirsutism, and 25 age matched non-hirsute control females. Height, body weight, body mass index (BMI), modified ferriman gallawy (mFG) scale were measured. Serum fasting glucose (SFG), and serum fasting insulin (SFI) were assessed. Homeostasis model assessment of insulin resistance (HOMA-IR) and serum adiponectin were evaluated by enzyme-linked immune-sorbent assay (ELISA). Serum total testosterone was measured for female patients with menstrual irregularities.
Result: The study revealed that females with hirsutism either with or without polycystic ovarion syndrome (PCO) had significantly lower serum Adiponectin level than controls (p<0.001). SFG, SFI and
HOMA-IR were significantly higher in patients with hirsutism than controls (p<0.001). HOMA-IR had a strong significantly positive correlation with BMI and mFG scale (p<0.001).