الفهرس 
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Abstract
Recurrent miscarriage (RM) is three or more consecutive miscarriages before the 20th week of gestation, which affects 0.5–1% of couples.
The causes of RM are classified as genetic, anatomical, endocrinological, immunological, microbiological, placental anomalies, hormonal problems, infections, smoking, alcohol consumption, exposure to environmental risk factors, psychological trauma, stressful life events, certain coagulation conditions. However many cases of miscarriages remain with no defined etiology.
Recent studies suggest that alterations in blood coagulations, such as antiphospholipid antibody syndrome and hereditary thrombogenic diseases are related to recurrent miscarriages.
Recurrent miscarriages is best investigated before another pregnancy occurs.
Transvaginal colour Doppler of the blood flow of the uterine arteries allows a non-invasive method for evaluating uterine perfusion. It is used in obstetrical ultrasound as a complementary tool to gain information about the presence, direction and velocity of blood flow.
Uterine receptivity is likely to be regulated by a number of factors including uterine perfusion and is of great importance in achieving a normal pregnancy.
In fact during the normal menstrual cycle, the impedance to uterine artery blood flow diminishes progressively during the luteal phase, reaching the lowest values in the period that temporally coincides with the implantation window.
Aim of the Work:
Reducing risk of recurrent miscarriage in the first trimester.
Methods:
This study was carried out in Obstetrics and Gynecology department, Zagazig University Hospitals included 120 women (60 women in each group) all fullfill the inclusion and exclusion criteria
All patients were subjected to the following:
1) History:
2) Clinical examination:
3) Pulsed color Doppler
Results
• No statistically significant difference between the studied groups in age distribution.
• No statistically significant difference between the studied groups in BMI distribution.
• There is high statistically significant difference between the studied groups in Resistance Index. Case group had significantly higher RI than control group.
• There was high statistically significant difference between the studied groups in endometrial thickness. Case group had significantly lower ET than control group.
• There was highly statistically significant difference between the studied groups in Pulsatility Index that is highly in case group.
• There was no statistical significant difference between the studied groups regarding FSH, level.
• There was no statistical significant difference between the studied groups regarding LH level.
• There was no statistical significant difference between the studied groups regarding TSH level.
• There was statistically significant negative correlation between recurrent Pregnancy loss in case group and Endometrial thickness (ET). On the other hand, there was a statistically significant positive correlation between recurrent Pregnancy loss in case group and Pulsatility Index (PI).