الفهرس 
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Abstract
Introduction : Androgenic alopecia (AGA) is the most common type of non-scaring hair loss affecting the scalp. It results from genetically determined end organ sensitivity to androgens and is characterized by miniaturization of the hair follicles. It usually begins between the age of 12 and 40 in both men and women and affects approximately 50% of the population before the age of 50. The amnion is the inner most layer of fetal membranes, which form a sac filled with the amniotic fluid, thus surrounding and protecting the embryo, the amniotic epithelial cells produce numerous cytokines and factors known to promote cell proliferation and differentiation. Specially, AF MSC produce various cytokines and chemokines, which are known to be important in normal wound healing and cosmetic dermatology, including interleukin IL-8, IL-6, tumor necrosis factor, TGF-β, VEGF and EGF. Microneedling is a simple office procedure that involves creating thousands of micro clefts through the epidermis in to the papillary dermis, so it enhances penetration of growth factors. Aim of the work : The aim of the work was to assess the efficacy and safety of irradiated amniotic collagen matrix (IACM) combined with microneedling in treatment of androgenic alopecia.