الفهرس 
AbstractOnly 14 pages are availabe for public view
 |  | from | 156 |  |  |
| | | from | 156 | | |
Abstract
Background: Breast-conserving surgery (BCS) is a common approach in the management of breast cancer. While it offers a more conservative alternative to mastectomy, BCS may introduce post-operative changes that require precise assessment. Dynamic Magnetic Resonance Imaging (MRI) and Diffusion-Weighted Imaging (DWI) have emerged as powerful tools for the assessment of these changes. Objectives: This study aimed to evaluate the ability of DWI, as a non-invasive sequence to detect suspected lesions and other post operative changes in breast cancer patients following conservative surgical procedures. Patients and methods: This was a prospective study that was performed on a selected group of 40 post operative breast cancer female patients at Radiology department at Meet Ghamr oncology center or Tanta University hospital who referred from surgical department and outpatient clinic. The included patients underwent complete history taking, clinical examination, and MRI assessment. Results: Malignant lesion had statistically significant higher hyperintense lesions in STIR images, also, malignant lesions showed statistically higher incidence of diffusion restriction as appeared from the DWI, and from the ADC (10-3 mm2/s) values. There were statistically significant differences between the two groups in the pattern of enhancement. ADC (10-3 mm2/s) values showed significant predictive value of the malignant lesions (p<0.001), with an area under curve (AUC) of 0.952. An ADC cutoff value of ≤1.13 could predict malignant lesions with a sensitivity of 90% and specificity of 93.9%. Conclusion: The combination of Dynamic MR and DWI represented a robust approach for post-operative evaluation. DWI, in particular, proved to be a powerful tool for characterizing breast lesions and distinguishing between benign and malignant cases, with a high level of sensitivity and specificity.