الفهرس | Only 14 pages are availabe for public view |
Abstract Bladder cancer is one of the top 10 most frequent malignancies globally with a high recurrence rate and an expensive treatment cost. The standard treatment protocol for bladder tumors is mainly based on the detrusor muscle invasion status. In recent years, DWI has been introduced in the evaluation of various abdominal lesions. These images are generated based on the quantifying diffusion of the water molecules in different tissues. In theory, diffusion is generally restricted in malignant tissues depending on their high cellularity and decreased extracellular space, leading to high signal intensity on Diffusion weighted imaging (DWI). The degree of diffusion is quantitatively calculated by the apparent diffusion coefficient (ADC) value and, this has been proven to be valuable in distinguishing benign and malignant lesions. Therefore, DWI is useful in detecting malignant tumors of the various abdominal organs including bladder carcinomas. So, this study aimed to evaluate the role of diffusion weighted magnetic resonance imaging (MRI-DWI) in evaluation of urinary bladder masses. It is a prospective study, which enrolled 40 patients with urinary bladder mass diagnosed by U/S or CT; 35 patients were males and 5 patients were females. Their ages ranged from 45-81 years with a mean ± SD of 60.500±10.221. All selected patients were subjected to: detailed history taking, renal functions test, review of all previous US and other radiological examination, MRI imaging which included (pre and post-contrast T1, T2, DWI, and ADC), and finally the data obtained from MR images compared with histopathological findings in all patients. |