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العنوان
Midazolam as Adjuvant to Bubpivacaine in Quadratuds Lumborum Block after Caesarean Section, Does it Offer Better Pain Control?
A Randomized Double Blind Clinical Trial/
المؤلف
Sefain, Elia Nagih Meshail,
هيئة الاعداد
باحث / إيليا ناجح مشيل سفين
مشرف / محمد أحمد محمد يوسف
مناقش / سامى عبدالرحمن
مناقش / مصطفى محمد أحمد محمد
الموضوع
Anesthesia and Intensive Care.
تاريخ النشر
2024.
عدد الصفحات
69 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
التخدير و علاج الألم
الناشر
تاريخ الإجازة
14/2/2024
مكان الإجازة
جامعة أسيوط - كلية الطب - Department of Anesthesia and Intensive Care
الفهرس
Only 14 pages are availabe for public view

from 69

from 69

Abstract

The Cesarean section is the most common obstetric and gynecological surgery carried out globally. it is gaining popularity year after year. Effective post-cesarean analgesia is important for mothers to take care of their children optimally. The analgesia must be safe for both the mother and the newborn. Opioids are classic post-operative analgesia but they have serious side effects such as pruritis, urinary retention, nausea, and vomiting that can lower patient satisfaction. New regional blocks were discovered and gained more popularity. New quadratus lumborum block, has increased postoperative pain relief when combined with other medications or used in place of spinal morphine after spinal anesthesia for cesarean delivery. It is effective in relieving somatic and visceral pain. The analgesic effect can be strengthened by using a variety of adjuvants. In peripheral and central neuraxial nerve blocks (intrathecal, epidural, and caudal), it has been shown that midazolam can enhance the analgesic efficacy of local anesthetics mediated by GABAergic and opioid receptors. We evaluated midazolam efficacy as an adjuvant to quadratus lumborum block in post-cesarean pain management. A double-blinded randomized controlled trial showed that the midazolam group showed a highly significant difference (P value < 0.001) in the post-operative Ketolac administration as rescue analgesia between the two groups. group II required less analgesic and more time for rescue analgesia when midazolam was added to bupivacaine. In comparison to group I, group II’s VAS score indicated a considerable reduction in pain within the first 12 hours. Each patient received a score of 2 on the Ramsay sedation scale in both groups. In both groups, the majority of patients reported satisfaction, and neither group experienced any side effects.