الفهرس | Only 14 pages are availabe for public view |
Abstract In the practice of a gastroenterologist, Irritable Bowel Syndrome is one of the most frequent GIT disorder.Gastroesophageal reflux disease is one of the common gastrointestinal diseases. It can be classified as erosive esophagitis and non-erosive reflux disease and depending on endoscopic picture. Functional esophageal disorders can present with typical esophageal symptoms that are not associated with structural, inflammatory, or a major motor abnormalityIn this study, we have investigated the comorbid disorders in esophagus in patient with IBS to assess the percentage of the entire spectrum of esophageal disorders and possible theories for overlap in IBS patients 254 patients with IBS were examined. 100 of them had upper GIT symptoms. To achieve this aim, these 100 patient underwent further investigations to assess esophageal disorders.For each patient: Full history taking, clinical examination, Upper endoscopy, Motility studies, and 24-hour pH monitoring were done.Our results showed that it was revealed that comorbid disorders of the esophagus in patients with IBS are: ERD in 27% of cases (while in 12% there is an intersection with hypersensitivity to reflux and functional heartburn), NERD in 24%, FED in 49% (while in 27% of cases they are represented by functional heartburn, in 9% by hypersensitivity to reflux, in 9% by a lump in the throat and in 4% by functional chest pain) FED was the most prevalent among different IBS subtypesFemale gender was most predominant in different IBS subtypes except IBS-C.H. pylori stool antigen was positive in 63.3% of FED patients, 51.9% of ERD patients, and 29.2% of NERD patients. ere was no significant difference between the final diagnoses of esophageal disorders according to gender. However, FED was prevalent at younger age than NERD and ERD. Also, NERD and ERD were prevalent at higher BMI than FED. |