الفهرس 
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Abstract
Helicobacter pylori (H. pylori) is a gram-negative bacillus responsible for one of the most common infections found in humans worldwide. The prevalence of the infection differs from country to another; it also differs from diagnostic test to another.
This study was done as across sectional study at Assiut university children hospital in the period from the 1st of January 2020 up to the end of December 2020. It included 92 children aged <18 years attending different health care facilities.
The study aimed to estimate prevalence of H. pylori using different diagnostic methods and to detect accuracy of these diagnostic methods.
Patients were divided into two groups: group I included non-symptomatic children and group II included children with symptoms suggestive of H. pylori infection.
Demographic data, socioeconomic status, and complaints were collected. Serum IgM and IgG and stool antigen were done for all patients, while endoscopic biopsy and histopathology was done in symptomatic patients requiring endoscopy.
It was found that prevalence of H. pylori infection using stool antigen test was 34%. The most accurate test was serum IgM however, it has low specificity.
The most frequent symptom found to be associated with the infection was found to be epigastric pain and the most common endoscopic finding was gastro-duodenitis.
We recommend that, in children it is better to depend on serum IgM as a non-invasive test to detect H. pylori infection as it has better sensitivity than serum IgG and stool antigen.