الفهرس 
Literature ReviewOnly 14 pages are availabe for public view
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Abstract
Multiple Sclerosis (MS) is one of the most common neurological disorders that impact the central nervous system. In this study, we investigated the role of neurotrophic long non-coding RNAs (lncRNAs) in MS. We analyzed the expression of three neurotrophic lncRNAs (BDNF-AS, BACE1-AS, and BC200) in MS patients with and without cognitive impairment. BACE1-AS and BC200 were consistently upregulated in MS patients, suggesting involvement in disease pathogenesis. BDNF-AS was downregulated in MS patients but displayed higher diagnostic accuracy. These findings shed light on the role of neurotrophic lnc RNAs in MS pathogenesis, cognitive impairment, and diagnostic potential.