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العنوان
Covid -19 Anti Immunoglobulin G Antibodies Serum LevelsAmong Health Care Workers in Suez Canal University Hospitaland Possible Side Effects Post Covid -19 Vaccine /
المؤلف
Mousa, Sara Sayed Saad
هيئة الاعداد
باحث / سارة سيد سعد موسي
مشرف / سارة سيد سعد موسي
مشرف / فادية مصطفي عطية
مشرف / وفاء حسن عمر
الموضوع
Endemic and Infectious Diseases
تاريخ النشر
2023
عدد الصفحات
120 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأمراض المعدية
تاريخ الإجازة
1/1/2023
مكان الإجازة
جامعة قناة السويس - كلية الطب - Endemic and Infectious Diseases
الفهرس
Only 14 pages are availabe for public view

from 141

from 141

Abstract

Healthcare workers are at higher risk of COVID-19 infection because of continuous exposure to patients. It is crucial for healthcare workers to achieve high COVID-19 vaccination rates for the protection of themselves and for people, especially patients, around them. Healthcare workers in correctional settings are an especially important population to be vaccinated because they work in closed environments filled with extremely vulnerable populations (e.g., individuals with high prevalence of chronic diseases).
The current study was a cross-sectional descriptive study, included health care workers in Suez Canal University Hospital, including doctors (physicians, surgeons), nurses, laboratory technicians and workers (Service). An interview- based questionnaire was used for data collection, and blood sample from each participant was collected, all samples had been screened for Covid-19 IgG titer by using kits of Roche Elecsys Anti-Sars-CoV-2 S Assay which is intended for the detection of antibodies (including IgG) to SARS-CoV-2 spike (S) protein receptor binding domain (RBD) in human serum and plasma.
A total of 141 serum samples of the health care workers received vaccines, with Cut off value of 0.8 U/ml according to the manufacturer’s instructions, there were significant rising of serum IgG titer post vaccine resembling about 96.5% of the studied group while 3.5% had negative values of serum IgG titer <0.4 U/ml.
The current study reported higher post-vaccination antibody response in those previously infected with COVID-19 resembling 58.2%.
The study included different types of vaccine m-RNA vaccine (Pfizer and Moderna), AstraZeneca vaccine, Sinopharm vaccine and Sinovac vaccine found that Oxford/AstraZeneca vaccine was the most frequent type to be received by HCWs (41.8%) followed by Sinovac vaccine (37.6%), Sinopharm (16.3%), Pfizer and Moderna (4.2%).
The mean titer levels of anti-RBD IgG antibodies in the Sinovac vaccinated