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العنوان
Short term study of Nano-Silver in Treatment of infected Diabetic foot ulcers /
المؤلف
Abid, Ahmed Abd El-Mohsen.
هيئة الاعداد
باحث / احمد عبدالمحسن عابد عبدالمحسن
مشرف / عثمان أبوالسباع عثمان
مشرف / مايكل صموئيل عياد
مشرف / مصطفى محمد عبدالغنى
مناقش / أيمن السيد حسب الله
مناقش / مصطفى ناجي الصناديقي
الموضوع
Foot - Ulcers. Diabetes - Complications. Diabetic Foot. Foot Ulcer.
تاريخ النشر
2023.
عدد الصفحات
107 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
جراحة
تاريخ الإجازة
19/9/2023
مكان الإجازة
جامعة المنيا - كلية الطب - الجراحة
الفهرس
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Abstract

Diabetic foot is a common condition caused by foot ulcers, infections, or deep tissue damage, and is associated with diabetic neuropathy and varying degrees of peripheral vascular lesions in the lower limbs. Nearly 15% of diabetic patients are at risk of developing foot ulcers as their disease progresses. Diabetic foot infections (DFIs) remain the most frequent diabetic complication requiring hospitalization and the most common precipitating event leading to lower extremity amputation .
The clinical use of nano-silver dressings helps to optimize the treatment process and improve the treatment efficacy in diabetic foot patients. It helps to eradicate the wound infection and promote the wound healing as well.
This is a single –center, prospective study that was conducted in Minia University Hospital , Vascular Surgery Unit including 40 patients presented with vascularized non ischemic DFU between June 2022 till June 2023.
The patients in this study had the following criteria:
• Type 1 or 2 diabetes treated by either oral hypoglycemic drugs or insulin.
• Presence of non-ischemic vascularized DFU after successful angioplasty .
• Ulcer or lesion present in the foot without extension beyond the ankle joint.
• diabetic foot wounds with infection, necrotic tissue or clean ulcer and proper debridement will be done if there is a need for it
The way of wound dressing : we used to clean the wound with sterile water then the wound was dried with a sterilized gauze dressing then topical nano-silver particles was applied to the wound and the silver particles were left for 10 minutes on the ulcer then crepe bandage was applicated . this process was done twice daily for 4 weeks.
Patients were examined after one week, 2 weeks and 4 weeks to assess the progress of eradication of infection and progress of wound healing.
Patients were be reviewed postoperatively at 3 months, to assess the outcome of these treatments or presence of any complications.
The main results of the study revealed that:
Nano-silver dressings are a novel form of broad-spectrum and safe, antibacterial dressing. It plays a significant role in the treatment of diabetic foot ulcers. About 82.5% of patients in one month follow up had good and healthy granulation tissue without infection and about 87.5% of patients in 3 month follow up had good response either by complete healing or by healthy granulation tissue with no complications.