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Abstract The marine environment has different ranges from nutrient-rich regions to nutritionally sparse locations where only a few organisms can survive. Also, it is involving special lighting conditions such as high salinity, high pressure, low temperature, that may contribute of significant differences between the enzymes generated by it and enzymes from terrestrial microorganisms. These features can be leading to enhanced marine microbial enzyme technology in recent years and the resulting valuable products. Recently, Many researchers have isolated a variety of enzymes with special activities from marine microorganisms (Zhang and Kim, 2010). Marine microorganisms represent approximately 70% of the total marine biomass within the ocean (Bar-On et al., 2018). In addition, marine microorganisms are important to nutrient recycling in ecosystems act as decomposers and responsible for nearly all photosynthesis that occurs in the ocean, as well as the cycling of carbon, nitrogen, phosphorus and other nutrients and trace elements (Sunagawa et al., 2015).Microbial enzymes play an important role as metabolic catalyst, leading to their use in numerous industries and application. Additionally, they have gained recognition globally for their widespread with numerous industrial commercial applications. Moreover, the most demand for industrial enzymes is on a continuous rise driven via a growing need for sustainable solutions (Adrio and Demain, 2014). Marine enzymes are capable of being active in large range of temperature, pH, high-salt concentration, organic solvents, surfactants, metal ions, and high incidence of light and pressure. In addition, constituting a group of exceptional biocatalysts, which applied in food industries, the biofuel, fine chemicals, and pharmaceuticals ( Dalmaso et al., 2015). |