الفهرس 
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Abstract
Introduction: Coronary artery disease (CAD) is the most prevalent group of cardiovascular disorders. There is a well-established link between smoking and coronary atherosclerosis. Smoking causes vascular endothelial dysfunction by various mechanisms. Aim of the work: The objective of this study is to describe the coronary angiographic pattern of lesions among smokers compared with nonsmokers. Subjects and methods: The study is descriptive observational comparative study that was conducted in the department of cardiovascular medicine department, Specialized Medical Hospital, Faculty of Medicine, Mansoura University, in the period from January 2022 to December 2022. The study was conducted on 150 patients who were admitted and underwent invasive coronary angiography. The patients were divided into two groups, 75 participants in the smoking group and 75 participants in non-smoking group. Results: The study results show that there is no significant difference between smokers and non-smokers patients regarding distribution of the affected arteries. LAD was the artery most involved in the smoking group.The prevalence of triple vessels was more common in smoking group compared to non-smoking group (26.7% versus 25.3%). Significant coronary lesions were more prevalent in smoking group. There is a statistical difference (p value = .014) between smoking and non-smoking patients regarding significance of coronary lesions. The diameter of stenosis was higher in smoking group (p value = .021). There is a statistically higher rate of coronary calcification among smokers (p value = .034). The following factors are associated with CAD and increased number of affected arteries: BMI, morbid obesity, smoking, total cholesterol, LDL, EF, and FS. Conclusion: Distribution of coronary atheromas doesn’t vary significantly in smokers; however higher incidence of triple vessel disease was found in smokers. Smoking is associated with higher degrees of lesion stenosis and calcification. Keywords: Smokers, nonsmokers, coronary angiograpy, coronary lesions, coronary artery disease, coronary stenosis