الفهرس 
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Abstract
In pharmaceutical science, quinoxaline is one of the most significant heterocyclic
scaffolds that are exposed to expansive research owed to its physicochemical features and
biological activities(1)
.
Quinoxalines, also called benzopyrazine, are nitrogen containing aromatic heterocycle results
from fusion of benzene ring to pyrazine moiety(2)
. Chemically, unsubstituted quinoxaline has a
melting point of 29-30 °C and a boiling point temperature of 108-111°/ 12 mm(3)
. It is soluble
in water and when handled with quaternizing agents such dimethyl sulphate or methyl p-toluene
sulphonate, it generates unstable monoquaternary sal