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Abstract
Background: Cardiac Resynchronization Therapy(CRT) has been proposed as atreatment of patients with idiopathic as well as ischemic left ventricular dysfunction with drug refractory heart failure and intra{u2013}or interventricular conduction delay. CRT improves heart failure , reduces the risk of death and improves the status of LV dysfunction. It is indicated in patients with LVEF {u2264} 35%, NYHA class II /III and ambulatory class IV, a wide QRS complex {u2265} 150 ms. Objective: to detect the patients subjected to CRT implantation at critical care department, monitoring and evaluating the patients as regards implantation, follow up, detection and management of complications and to detect the effect of CRT on clinical outcome and echocardiographic changes in patients subjected to CRT within months after implantation. Results: The study included 180 patients were subjected to CRT implantation from January 2007 till December 2013, There was a significant improvement in EF %, left ventricular dimensions, width of QRS complex and NYHA class (P-value<0.001) six months after CRT implantation. There was a significant improvement in EF% as the percentage of decrease of QRS complex width increased after CRT implantation. About 58 % of patients were responders and 42 % were not responders according to improvement in EF{u2265}10% and improvement in NYHA class {u2265} 1 class. The rate of complications was low (13.8%) and all complications were managed successfully