الفهرس 
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Abstract
Hair samples are one of the most important resources in the forensic
analysis of crime scenes, often providing valuable information that can lead to
the identification of a suspect or a victim. In this study, Thirty Wistar male rats
were grouped into three groups and used for HPTLC quantitative evaluation of
Cannabis and Pregabalin residues in hair and serum in addition to screening of
their toxicological effects. First group kept as negative control, second group
(Cannabis group, administered Cannabis by gastric tube at a dose of 3 mg/kg b.
wt.) and third group (Pregabalin group, administered Pregabalin by gastric tube
at a dose of 30 mg/kg b.wt.) daily for eight weeks. Residues of Cannabis and
Pregabalin were evaluated by HPTLC, Oxidative stress parameters were
analyzed in serum. Histopathological examination of the kidney, liver and brain
samples was done. Results revealed that Cannabis and Pregabalin were both
deposited in hair and serum compared with control groups; the toxicological
effect was more marked in Cannabis group. Using of hair samples can be added
besides blood and urine samples for drug addicts tests.