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Abstract compared with those of all other corresponding groups in the acute and subacute experiments. In subacute experiments in the serum of rats in groups IX, the AFB1 residue in the serum exhibited a significant direct relationship with the levels of MDA, and this relationship was accompanied by a positive significant correlation coefficient, whereas the levels of GSH and activities of CAT, SOD, and GR showed significant inverse relationships and were associated with a significant negative correlation coefficient. The results of acute and subacute experiments in serum of rats in groups V and X, the levels of MDA, GSH, and activities of CAT, SOD, and GR didn’t differ significantly when compared with the corresponding groups of I, II, III, and VI, VII, and VIII, respectively. This means that the levels of MDA, GSH, and the activities of CAT, SOD, and GR were recovered to their normal levels. from the above-mentioned results, we can conclude that barley is an excellent antiaflatoxosis which plays a significant role in the detoxification and elimination of AFB1 from all the tissues. In turn, all normal toxicokinetic parameters of AFB1 (uptake, distribution, and bioaccumulation) and its toxicodynamics (levels of MDA, GSH, and activities of CAT, SOD, and GR in serum) were markedly recovered in the serum of rats in groups V and X as a direct response to treatments with barley during the acute or subacute experimentations. |