Search In this Thesis
   Search In this Thesis  
العنوان
Ameliorative Role Of Barley Against Aflatoixn B1 In Male Albino Rats /
المؤلف
Mohamed Ramadan Elgohary Ali Elsharkawy;
هيئة الاعداد
باحث / Mohamed Ramadan Elgohary Ali Elsharkawy
مشرف / Gamal Mohamed Morsy
مشرف / Atef Abdel-Moneem Ali
مشرف / Shaaban Mostafa Abdel-Fattah
الموضوع
Integrated Molecular Physiology
تاريخ النشر
2022.
عدد الصفحات
92 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الصحة وعلم السموم والطفرات
تاريخ الإجازة
16/7/2022
مكان الإجازة
جامعة القاهرة - كلية العلوم - Physiology and Toxicology, Zoology
الفهرس
Only 14 pages are availabe for public view

from 129

from 129

Abstract

compared with those of all other corresponding groups in the acute and subacute experiments. In subacute experiments in the serum of rats in groups IX, the AFB1 residue in the serum exhibited a significant direct relationship with the levels of MDA, and this relationship was accompanied by a positive significant correlation coefficient, whereas the levels of GSH and activities of CAT, SOD, and GR showed significant inverse relationships and were associated with a significant negative correlation coefficient.
The results of acute and subacute experiments in serum of rats in groups V and X, the levels of MDA, GSH, and activities of CAT, SOD, and GR didn’t differ significantly when compared with the corresponding groups of I, II, III, and VI, VII, and VIII, respectively. This means that the levels of MDA, GSH, and the activities of CAT, SOD, and GR were recovered to their normal levels.
from the above-mentioned results, we can conclude that barley is an excellent antiaflatoxosis which plays a significant role in the detoxification and elimination of AFB1 from all the tissues. In turn, all normal toxicokinetic parameters of AFB1 (uptake, distribution, and bioaccumulation) and its toxicodynamics (levels of MDA, GSH, and activities of CAT, SOD, and GR in serum) were markedly recovered in the serum of rats in groups V and X as a direct response to treatments with barley during the acute or subacute experimentations.