الفهرس 
The value of serum progesterone level on the day of frozen embryo transfer on the clinical pregnancy rate in frozen-thawed IVF cycles
LIST OF CONTENTSOnly 14 pages are availabe for public view
 |  | from | 81 |  |  |
| | | from | 81 | | |
Abstract
Frozen embryo transfer (FET) is a procedure used for the storage and transfer of excess embryos obtained during in vitro fertilization or intracytoplasmic sperm injection cycles, The number of frozen-warmed embryo transfer (FET) procedure has been increasing worldwide in the last decade. The main reasons underlying this circumstance are improvements in controlled ovarian hyperstimulation (COH) regimens, higher embryo survival rates after the implementation of vitrification in the laboratory and elective single embryo transfer (ET) policies, Progesterone is required for successful embryonic implantation into the endometrium and maintenance of the pregnancy in natural cycles, fresh in vitro fertilization cycles, and frozen embryo transfer (FET) cycles. With the progressive increase in the use of frozen embryo transfer, it has become essential to find ways of optimizing the outcomes of this procedure. Aim and objectives; to assess the relationship between serum progesterone level on the day of frozen embryo transfer and clinical pregnancy rate, Subjects and methods; This prospective study was conducted at Cairo University Obstetrics & Gynecology Hospital, Al Kasr Al Ainy, Assisted Reproduction Unit. This study included women aged 18 to 40 years who were prepared for frozen embryo transfer according to inclusion and exclusion criteria. The duration of the study was1 year and 6 months, Result; the studied cases were divided into two groups regarding progesterone level, group (1) included those women that recorded progesterone levels<9.2 ng/mL and group (2) who had recorded progesterone levels ≥ 9.2 ng/mL on day of embryo transfer. Regarding outcome BHCG, clinical pregnancy and Ongoing pregnancy were compared in the studied groups. There was statistically significant increase the prevalence of positive B-HCG, clinical pregnancy rate and ongoing pregnancy rate in group (2) who had progesterone level ≥ 9.2 compared to group (1) who had progesterone level < 9.2 (p=0.002, 0.005 & 0.012 respectively).This was demonstrated across positive B-HCG (69.5% vs 47.4%., p = 0.002), clinical pregnancy rates (67.4% vs 47.4%., p = 0.005), and ongoing pregnancy rates (48.4% vs 30.5%. ,p = 0.012).