الفهرس | Only 14 pages are availabe for public view |
Abstract The effect of elevated levels of serum fats -hyperlipidemia- on the long-term implant stability and bone quality has been heavily examined in animal-model studies. This human-based case series aimed at clinically and radiographically evaluating implant stability and the changes in bone density in patients with high lipid profile. Twelve participants, each had a single healed bony site which indicated for implantation together with high serum fasting (Low-density lipoprotein) LDL level (≥160 mg/dl) were included in this study. The differences between the clinical implant stability values (ISQ) which were measured using the Resonance Frequency Analysis (RFA) method, and the radiographic CBCT changes were recorded at baseline and six months post-implant insertion. In addition, the Patient-reported outcomes (PROs) including pain, swelling as well as patient satisfaction were evaluated via NRS, VRS based questionnaires. All patients showed successful osseointegration after six months. There was a significant increase of implant stability after 6 months from (65.92 پ} 6.39 ISQ) to (74.42پ}6.20 ISQ) (p<0.001). The mean linear and volumetric radiographic crestal bone level at the baseline (238.49پ}55.62 mm2) were significantly higher than that found after 6 months (204.94پ}72.95 mm2) (p=0.018). Regarding bone density, there was no significant difference between values found at baseline (586.20پ}239.92 HU) and after 6 months (657.90پ}162.14 HU) (p=0.121). However, based on the results obtained and the limitations of this very first clinical study on the correlation between dental implant stability and hyperlipidemia, authors found that hyperlipidemia alone is not considered a major risk factor for dental implant stability. |