الفهرس | Only 14 pages are availabe for public view |
Abstract In modern human history, infectious diseases have posed a threat to public health several times, coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has emerged as a global public health crisis. Identification of demographic, laboratory and radiological predictors of progression of COVID-19 infection in Egyptian patients. A special concern is focused on the poor prognostic factors associated with mortality, this will help us to classify and monitor COVID-19 patients to deliver best medical care in order to decrease mortality and morbidity in Egyptian patients. A single-center, retrospective cohort study. This study was conducted in Almaza Fever Hospital after obtaining approval from the Research Ethical Committee. Sample population: Patients were classified as per the attached protocol of MOHP (Jan 2022) into 2 groups: Mild-moderate cases and severe cases; group I: Mild-moderate disease patients (204) known positive COVID-19 infection, clinical features include respiratory rate (20-30) breath/min, fever above 38, myalgia, sore throat, oxygen saturation above 92 %. No signs of dehydration, sepsis, or shortness of breath. group II: Severe disease patients (121); clinical features include respiratory rate above 30 breaths/min, signs of severe respiratory distress (dyspnea, orthopnea) oxygen saturation below 92 %. It was found that older age was prevalent among severe disease patients and non-survivors, mean age was (66.22 ± 12.18 and 70.69 ± 9.87) respectively, also found that mean age among severe disease patients (70.5 ±15.7). The current study found that underlying co-morbidities more prevalent among severe disease patients than mild-moderate disease patients 103 (85.1%) from a total number of 121 severe disease patients with a statistically significant difference. Also 22 (75.86%) of total 29 non-survivors had one or more of co-morbidities but it doesn’t reach the level of significance. the most prevalent co-morbidities in the study group were Diabetes, Hypertension, Ischemic heart disease, CLD, and CKD. |