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Abstract This study was conducted to determine the effect of vestibular rehabilitation on premenstrual symptoms and physical, emotional and functional impacts related to vestibular disorders in adolescent females diagnosed with premenstrual syndrome (PMS). Forty adolescent females participated in this study. They were randomly distributed into two groups: control group (19 adolescents) received calcium (1200 mg), vitamin B6 (50 mg) and low salt diet daily for 4 weeks, and the study group (21 adolescents) received the same medical supplements, low salt diet, in addition to sessions of vestibular rehabilitation training daily for 4 weeks. Premenstrual symptoms were evaluated using premenstrual syndrome questionnaire (PMSQ) and the vestibular complains were assessed using Dizziness handicap inventory questionnaire (DHIQ) at the starting and after the end of the treatment course. Results revealed that the study group showed a statistically highly significant decrease(P=0.001) in premenstrual syndrome {u2013} anxiety(PMS-A), premenstrual syndrome {u2013} craving (PMS-C), premenstrual syndrome {u2013} depression (PMS-D), premenstrual syndrome {u2013} hydration (PMS-H), premenstrual syndrome related to other symptoms, premenstrual syndrome symptoms during first two days, as well as physical, emotional ,and functional impacts related to vestibular complains, while the control group showed a statistically significant decrease only in PMS-H.(P=0.047) and a non-significant change in PMS-A (P=0.205), PMS-C (P= 0. 431), PMS-D (P=0.832), other symptoms (P=0.070), symptoms during first two days(P=0.102), as well as physical symptoms(P=0.892), emotional (P=0.102), functional impacts (P=0.527) after treatment. Compared to the control group, the study group showed a statistically highly significant decrease in PMS-A(P=0.001), PMS-D (P=0.004), other symptoms (P=0.001), symptoms during first two days (P=0.001), and physical (P=0.001), emotional (P=0.001), and functional impacts (P=0.001) related to vestibular disorders and a significant decrease in PMS-C (P= 0.017) and PMS-H (P= 0.015).Thus, the vestibular rehabilitation is an effective treatment for improving premenstrual symptoms, as well as physical, emotional and functional impacts related to vestibular disorders in adolescents with PMS |