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العنوان
Impacts of some genetics variation on coronary artery disease (CAD) in controls and Egyptian patients /
الناشر
Soheir Mahmoud Mahmoud Ibrahim ,
المؤلف
Soheir Mahmoud Mahmoud Ibrahim
هيئة الاعداد
باحث / Soheir Mahmoud Mahmoud Ibrahim
مشرف / Mahmoud Ahmed Amer
مشرف / Enas AbdelLatif Ahmed
مشرف / Ashraf Huossen Abdelmohsen
تاريخ النشر
2015
عدد الصفحات
145 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
علم الحيوان والطب البيطري
تاريخ الإجازة
11/5/2015
مكان الإجازة
جامعة القاهرة - كلية العلوم - Zoology Department
الفهرس
Only 14 pages are availabe for public view

from 135

from 135

Abstract

The present study investigated the relationship between the genetic polymorphisms of Angiotensin-converting enzyme (ACE) and Matrix metalloproteinase 3 (MMP-3) genes in Coronary artery disease (CAD).ACE (I/D) and MMP3 (5A/6A) polymorphism was detected using polymerase chain reaction (PCR). The frequencies of D/D, I/D, and I/I genotypes in CAD compared to control group were significantly different (P=<0.05), and the frequencies of 6A/6A, 5A/5A, and 5A/6A genotypes in CAD compared to control group were significantly different (P=<0.05). The D/D polymorphism of the ACE gene and 5A/6A polymorphism of the MMP3 gene is strongly associated with Coronary artery diseases (CAD) in the Egyptian population