الفهرس 
Prospective randomized trial of adjuvant radiotherapy versus observation after radical cystectomy in high-risk urothelial bladder cancer
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Abstract
Background and Purpose: Radical cystectomy with pelvic
lymphadenectomy remains the standard of care for non-metastatic invasive
bladder cancer. The loco-regional recurrence (LRR) rates remain a great
burden, even during the era of neoadjuvant chemotherapy (NAC). Our aim is
to clarify the benefit of adjuvant radiotherapy while limiting gastrointestinal
toxicities for patients with pathological high-risk bladder cancer through
assessing locoregional control (LRC). Our secondary end points are to prove
the superiority of adjuvant radiotherapy in disease free survival, overall
survival, distant metastasis free period and the relation between the local
control and development of secondary distant metastasis.