الفهرس | Only 14 pages are availabe for public view |
Abstract Taste is considered a parameter of the most crucial parameters which is significantly affecting patient compliance in case of drugs with poor palatability. Taste masking is a major challenge for the development of orally ingested active pharmaceutical constituent in the field of the pharmaceutical industry. Numerous conventional taste masking techniques have been extensively studied. Affecting the drug solubility or release is a major concern of conventional taste masking techniques. Recently, many nanocarrier systems have been introduced, claiming the advantage of effective taste masking without affecting either the drug solubility or the release. In order to enhance taste of oral diclofenac potassium (DP) to enhance its compliance, the current study aims to prepare DP liposomes as nanocarrier system for taste masking. For achieving this goal, the work in this dissertation will be divided into the following chapters: Chapter (I): Development of Novel Technique for the Preparation of Diclofenac Potassium Liposomes and Their characterization. Chapter (II): Formulation and Evaluation of Powder for Oral Reconstituted Suspension of Diclofenac Potassium liposomes |