الفهرس 
TITLE PAGEOnly 14 pages are availabe for public view
 |  | from | 92 |  |  |
| | | from | 92 | | |
Abstract
Context: Refractive errors are an important cause of vision impairment. Topographic-guided ablation by femtosecond laser-assisted in-situ keratomileusis (FS-LASIK) can alleviate some of the limitations of Wavefront-guided LASIK. Aim: This study aimed to compare the efficacy and safety of FS-LASIK and conventional LASIK in myopia cases. Settings and Design Methods: This study was conducted in Cairo, Egypt, upon 100 individuals with 200 eyes, from Jan-2020 to Jan-2021. They are grouped into FS-LASIK group (n=100 eyes) and conventional LASIK (n=100 eyes). Methods and Material: The study used Allegro topolyzerContoura upon 100 individuals with 200 eyes. They are grouped into FS-LASIK group (n=100 eyes) and conventional LASIK (n=100 eyes). Statistical analysis used: Chi-square test and ANOVA Results and conclusion: At the baseline, there was no significant (p=0.324) difference in central corneal thickness between the FS-LASIK group 542.17±25.93 and conventional-LASIK group 545.64±23.62. They were comparable as regard K1 (p=0.994) 43.92±1.95 and 43.92±1.90, and in K2 (p=0.789) 44.89±4.54 and 44.71±4.64 in the FS-LASIK group and the conventional-LASIK group, respectively. There is no significant difference in vision in the pre-operative, after one-month and after three-months (p-values > 0.05) post operatively. In the second day postoperative, there was significant reduction of vision in conventional-LASIK group compared to FS-LASIK group (p<0.001). The proportion of coma and spherical HOAs in both groups were increased dramatically after one week and decreased gradually at one month and 3-months evaluations. The proportions of trefoil and sixth foil aberrations were decreased after the procedure. In conclusion, FS-LASIK using Contoura demonstrated good safety, efficacy, and predictability in treating myopia and myopic astigmatism in both mild and moderate cases.