الفهرس 
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Abstract
Summary
Sudden deafness is characterized by sensorineural hearing loss (HL) of 30 dB HL or more over at least 3 sequential frequency steps in the standard pure-tone audiogram, which develops over a period ranging from a few hours to 3 days in otherwise normally hearing, healthy individuals. Although sudden deafness is a well-recognized condition.
This study was conducted at Beni-Suef University Hospital to compare the therapeutic efficacy of different Intra-tympanic Injection of steroids including Methylprednisolone and dexamethasone in the treatment of ISSHL.
The mean age of patients managed with methylprednisolone was 33.1±11.6 and most of them were females (55%). Similarly, the mean age of patients managed with dexamethasone was 33.6±12.3 but most of them were males (65%). The majority of cases demonstrated unilateral affection in (85%) in methylprednisolone group affecting the left ear in (56.5%) and (75%) in dexamethasone group affecting the right ear in (52%).
Our study found that there was statistically insignificant higher complete and partial recovery in Methylprednisolone than Dexamethasone groups. In methylprednisolone group (17.4%) showed partial recovery compared to (16%) in dexamethasone group. Also, (21.7%) in methylprednisolone group showed complete recovery compared to (12%) in dexamethasone group.
As regards to the speech discrimination, according to the grade of ISSHL, the majority of patients in both groups were grade II and III with a mean speech discrimination 68.1%±16.8% for methylprednisolone group and 64.9%±29.6% for dexamethasone group.
The mean speech discrimination after injection was 74.3%±19.3% in methylprednisolone group and 69.6%±31.6% in dexamethasone group. There was statistically insignificant difference between Methylprednisolone and Dexamethasone groups regarding the speech discrimination after injection.
There was insignificant improvement in speech discrimination in both groups however the absolute mean difference was higher in Methylprednisolone than Dexamethasone group.
Also, there was statistically insignificant difference between Methylprednisolone than Dexamethasone groups regarding the percentage of increase of the speech discrimination after injection however it was higher in Methylprednisolone.