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Abstract Because of the great growing in mobile phone communications and their services, it was so important to study their electromagnetic waves (EMW) effects on melatonin and biogenic amines (epinephrine, norepinephrine, dopamine, serotonin, and histamine) of the neonatal rat brains during the prenatal period until different postnatal days (P1, P7, P14, P21 and P28). Female pregnant rats were exposed to EMW from mobile phone antenna (3G SAR 1.25 W/kg body) and the irradiation continued until the 28th day of postpartum time. After parturition, neonatal rats were decapitated under red light and their brains were removed. Melatonin and biogenic amines concentrations were estimated by HPLC (UV detector). Results showed that in the group of neonatal rats that exposed to EMW, there was a significant (P< 0.05) increase in melatonin levels accompanied with a significant decrease in dopamine, histamine, norepinephrine and epinephrine in comparison to normal group. Exposure to EMW may cause many disturbances in the nervous system of the neonatal rats |