الفهرس | Only 14 pages are availabe for public view |
Abstract Background: Warts are a benign epithelial proliferation of the skin and mucosa that are caused by infection with human papillomavirus (HPV).Topical and intralesional vitamin D were used in treating viral warts, suggesting the importance role of vitamin D in viral warts. Objectives: The aim of this study was to evaluate the serum levels of 25hydroxy vitamin D(25OHD) in Egyptian patients diagnosed with viral warts as compared with healthy controls to investigate the potential role of vitamin D in the viral warts. Patients and methods: This study included 40 patients with viral warts and 47 age and sex matched healthy controls. Blood samples were taken from all participants for the detection of serum 25 OH D levels by enzyme linked immunosorbent assay (ELISA). Results: The present study showed a statistically significant decrease in the serum 25-OH vitamin D levels in viral warts patients when compared to controls (p=0.001). In addition, there was a statistically significant difference between patients and controls regarding vitamin D status (p=0.001), as viral warts patients had a more deficient pattern of vitamin D status than controls. Conclusion: The present study revealed low levels of serum vitamin D in warts patients, suggesting a possible role for vitamin D as supplement treating viral warts patients |