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العنوان
Anti-inflammatory and cardiovascular protective potentials of flaxseed and sun flower seeds oils against atherosclerosis in rats /
الناشر
Hanan Hasan Ahmad ,
المؤلف
Hanan Hasan Ahmad
هيئة الاعداد
باحث / Hanan Hasan Ahmad
مشرف / Muhammad Tawfeeq Abdalaziz
مشرف / Mohammad Farraj Elyamany
مشرف / Zeinab Yousef Ali
تاريخ النشر
2017
عدد الصفحات
129 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الصيدلة ، علم السموم والصيدلانيات (المتنوعة)
تاريخ الإجازة
18/2/2018
مكان الإجازة
جامعة القاهرة - كلية الصيدلة - Pharmacology and Toxicology
الفهرس
Only 14 pages are availabe for public view

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Abstract

Abstract: The present study was aimed to assessment of the possible cardiovascular protective potential of flaxseed (FO) and sun flower (SFO) seeds oils againstatherosclerosis in rats induced by high cholesterol diet (HCD), the results were compared with a reference drug for the treatment of atherosclerosis (rosuvastatin) and lasted for 12 weeks. The gas chromatography was used to estimate the percentage of fatty acids andvitamin E in FO and SFO. Our result demonstrated that there was generally dose-response beneficial decrease in the cardiac diagnostic enzymes, inflammatory response, and markers of oxidative stress after administration of flax seed oil and rosuvastatin to hyperlipidemic rats. These biochemical results were corroborated with the histological studies of aortic tissues. Flaxseed oil has more effective protection than sunflower against oxidative cardiovascular injure induced by feeding on HCD