الفهرس 
H EPATITIS C V IRUSOnly 14 pages are availabe for public view
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Abstract
ABSTRACT
Serum levels of Zn, Vit. D, and IL-17 were assessed in the patients group and subgroups. Patients lymphocytes were activated in vitro in the presence or absence of Zn or Vit.D3 in 2 different concentrations (low and high), and then intracellular IL-17 production was assessed using flow cytometry.
Our results showed that Zn and Vit. D were significantly decreased in HCV patients. Increasing disease severity leads to more reduction in Zn level opposed by increasing IL-17 level.
Zn potently reduced IL-17 production in a dose-related fashion. Vit. D apparently increases IL17 expression, it is unclear whether it is due to its toxic effect on cell count or lack of definite association between Vit. D and both IL-17 and disease severity.