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Abstract Fungal keratitis (FK) was first documented in 1879 and incidence has been increasing for the past 30 years. It is accountable for 40% to 50% of all isolated keratitis cases. FK develops rapidly and can lead to corneal ulcers and vision loss, so early diagnosis and prompt treatment are essential to prevent long-term complications.1 Mycotic keratitis is a disease caused by fungal invasion into the corneal stroma. It is an exogenous infection, attacking the injured corneal epithelium, and establishes the fungal growth within the collagen bound lamellae of stromal layer of cornea. Mycotic keratitis is considered to be a resistant corneal ulcer, which possesses aggressive microbial growth, and becomes not responding to conventional treatments for at least one week, or more, and even becomes worse due to continued fungal growth, and toxification of cornea by drugs, and fungal secretions. 2 Healthy cornea can be rarely infected and invaded by microorganisms and commonly predisposed by trauma that produces corneal abrasion and discontinuity of corneal epithelium. |