الفهرس 
Effect of CPP-ACP pastes with/without fluoride on white spot lesion progression, salivary PH and fluoride release in high caries risk patients : A randomized clinical trial
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Abstract
Aim: To evaluate the efficacy of casein phosphopeptide amorphous calcium phosphate with and without fluoride on WSL progression, salivary pH and fluoride ion release compared to fluoridated toothpaste on high caries risk patients. Methodology: A total number of 51 high caries risk participants with occlusal white spot lesions (WSLs) determined by VistaCam were randomly assessed into 3 equal groups (n=17) ; group 1: CPPACP + Fluoridated toothpaste; group 2: CPP-ACFP + Fluoridated toothpaste; group 3: Fluoridated toothpaste only. WSLs progression were assessed at baseline, 1 month and 6 months. The pH values and fluoride ion release assessments were done at baseline, immediate after application, 1 day, 1 week and 1 month.The pretreatment and the post intervention VistaCam scores, salivary pH and fluoride ion release were tabulated and subjected to statistical analysis. Results: There was no statistically significant difference in VistaCam scores between the tested periods with Tooth Mousse, MI Paste Plus and Fluoridated tooth paste.There was no statistically significant difference in salivary pH between different evaluation times with Tooth Mousse and control group. MI paste plus showed a statistically significant increase in pH value. Regarding Fluoride ion release, there was a statistically significant difference between different evaluation periods with MI Paste Plus only. Also, intergroup comparison showed a statistically significant difference in each assessment period