الفهرس 
Title : Combined Fractional Micro-Needling Radiofrequency and Tranexamic Acid Injection versus Combined Fractional Micro-Needling Radiofrequency and Vitamin C Injection for Face Rejuvenation: A Split Face Comparative Study
AbstractOnly 14 pages are availabe for public view
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Abstract
Background:The continuous and increasing urge for youthful looking skin has become the drive for constant innovation of minimally invasive procedures with maximal results for face rejuvenation. Aim: Comparing the efficacy of combined fractional micro-needling radiofrequency and tranexamic acid injection and combined fractional micro-needling radiofrequency and vitamin C injection, and assess whether one method will give superior results. Patients and methods: Twenty adult females with ages ranging from 33 years to 50 years, with Fitzpatrick skin photo-type II, III, and IV and Glogau wrinkle scale II and III were enrolled in this study. They underwent a split face therapy where the right side was assigned to combined fractional micro-needling radiofrequency and tranexamic acid (500mg/5ml) injection (group A), and the left side was assigned to combined fractional micro-needling radiofrequency and vitamin C injection (ascorbic acid 20%) (group B). Patients received 2 sessions at one-month intervals. Evaluation was carried out using global aesthetic improvement scale (GAIS), optical coherence tomography (OCT) and patient satisfaction level (PSL). Patients were followed up at 6 weeks. Results: Both procedures yielded significant improvement regarding GAIS and PSL. They also produced significant increase of dermal thickness measured by OCT. Average GAIS score was significantly higher in group A. PSL showed no significant difference between group A and B, but a higher mean with group B. Dermal thickness measured by OCT was significantly higher in group B at six weeks after the 2nd (last) session