الفهرس 
Impact of mechanical ventilation on neurobehavioral maturity of the preterm infant
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Abstract
Background: premature newborns face stressful situations and many influencers from birth until reach medical stability in NICU. Medical interventions as mechanical ventilation influence the process of neurobehavioral maturation putting the premature newborn at risk of atypical developmental outcomes. Purpose: To determine the impact of mechanical ventilation on the neurobehavioral maturity of the preterm infants and the correlation between mechanical ventilation and neurobehavioral maturity domains. Subjects: one group of sixty four preterm infants who received mechanical ventilation (33 girls and 31 boys), aged from 32 weeks{u2019} to less than 37 weeks CA, with (NMI) from 2 to 5 and (ICS) scoring 9 or above, recruited from NICUs of Cairo university hospitals. Methods: The study group was assessed in one shot after being weaned from the ventilatory support and achieving medical stability, using Neurobehavioral assessment of the preterm infant (NAPI). Results: There was statistically significant difference in popliteal angle and alertness and orientation domains of the neurobehavioral maturity of study group at mean age 35 weeks CA (p = 0.014) when compared to norm reference at same age. There were moderate to strong correlations of ventilation length of stay and severity of illness with tone maturation, irritability and cry quality. Conclusion: The findings of this study indicated that the premature newborns who received ventilatory support are at risk for worse developmental outcomes and need longitudinal follow up until term