الفهرس 
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Abstract
The aim of the study was to describe the prevalence of oral and para-oral lymphomas in Cairo governorate’s educational hospitals and institutions throughout the ten-year period from 2010 till 2019 and to analyze relations between age, gender, site and types of lymphoma.
Methodology: Histopathological reports of patients diagnosed with oral and para-oral lymphomas within the 10-year period from 2010 to 2019 were retrospectively retrieved from archives of multiple educational hospitals and institutions in Cairo governorate. Data regarding age, gender, site and diagnosis was collected from the reports. The diagnoses were reviewed according to the most recent 2017 WHO classification. The data gathered was entered into Microsoft Excel spreadsheets and transferred to a statistical software program for analysis.
Results: 362 cases of oral and para-oral lymphomas were found which constituted 2.86 % of oral and para-oral lesions. The mean age of patients was 54 (standard deviation 18.5), the median age was 56 (age range 3.5-92 years). There was no significant gender predilection. Tonsil was the most commonly affected site, followed by the parotid gland. Intra-oral affection was less frequent, with the hard palate being the most common intra-oral site. Non-Hodgkin lymphoma was more common than Hodgkin lymphoma in oral and para-oral sites. Diffuse large B-cell lymphoma was the most common histologic subtype with a predilection for tonsils, followed by marginal zone lymphoma of mucosa-associated lymphoid tissue which was predominant in salivary glands. Forecasting for prevalence of oral and para-oral lymphomas through five years (2020 to 2024) showed a predicted increase in prevalence.
Conclusions: Lymphomas can occur in oral and para-oral sites, as they constituted 2.86 % of lesions. The tonsil was the most commonly affected site, while hard palate was the most common intra-oral site. Diffuse large B-cell lymphoma was the most frequent histological subtype, consistent with majority of other studies. Since no previous studies have been set up to describe the epidemiology of oral and para-oral lymphomas in Egypt, this study serves as a stepping-stone towards understanding the prevalence of lymphomas in Egypt.