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Abstract IPF is a specific form of chronic, progressive, fibrosing interstitial pneumonia of unknown cause and defined by the histopathologic and/or radiologic pattern of UIP.It commonly occurs in older smokers males with unexplained chronic exertional dyspnea, cough, bibasilar inspiratory crackles, and digital clubbing that occur without any symptoms that may suggest other alternative diagnosis.(18)Pulmonary function tests are an important tool in diagnosis and monitoring of patients with IPF. Spirometry, lung volumes and DLCO should be measured in all patients.These studies typically identify a reduced forced vital capacity(FVC), a reduced total lung capacity, and a reduction in DLCO. |