الفهرس | Only 14 pages are availabe for public view |
Abstract Infertility impacts about 13-14% of reproductive-aged couples. Since the institution of IVF, it became apparent that just about 1/2 of the couples failed to get successful fertilization, this is known as unexplained infertility. The use of testicular in preference over ejaculated sperm for intracytoplasmic sperm injection (ICSI) has gained more attention thanks to reports of higher successful pregnancy outcomes using testicular sperm for cases of male factor infertility The aim of this study is to assess the role of testicular sperm usage after repeated ICSI failures using ejaculated sperm. This retrospective study included 110 patients with repeated failed ICSI were allocated into two groups retrospectively, one of them underwent testicular ICSI and the other underwent ejaculate ICSI at El-Nada and Bedaya Fertility centers throughout 2018. Data collected retrospectively & The two groups were well matched regarding their age of wife, age of husband, duration of marriage, history of previous marriage and previous children. When the results were analyzed it was found that ICSI using testicular extracted sperm should be considered superior to ICSI using ejaculated sperm in the treatment plan of infertile couples with a history of repeated ICSI failures and increased SDF may be the main cause of repeated failures of ICSI using ejaculated sperm which remains to be proved by various studies. Also the study showed that higher pregnancy and live birth rates are associated more with higher testicular biopsy motility per drop, testicular biopsy concentration, Number of embryos and the fertilization rate. |