الفهرس 
PhosphidesOnly 14 pages are availabe for public view
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Abstract
Phosphides are potent pesticides that are used for crop protection during storage and as rodenticides. They have currently aroused interest with the increasing number of poisoned cases in the past four decades. Studies show AlP is a preferred poison for committing suicide since it is easy to buy, cheap, and of known lethality. Death rates caused by AlP poisoning have been demonstrated as high as 70–100%. In Egypt, phosphide poisoning is an alarming health problem with escalating rates of poisoning especially due to the lack of control on selling AlP tablets. Another factor is the unawareness of the people of how dangerous AlP is. Mitochondrial affection, oxidative stress, hemoglobin involvement, and glucose metabolism affection were all proposed as possible mechanisms of toxicity of phosphides. However, the exact mechanism is not well-established. Among the proposed mechanisms, inhibition of the cholinesterase enzyme was reported in the literature. This current study aimed to evaluate the effect of acute phosphide poisoning on AChE and BuChE levels as a possible mechanism of toxicity. The study was approved by the Research Ethical Committee, Faculty of Medicine, Tanta University (approval number: 32893/1/19). The present study was carried out on eighty subjects. group 1 consisted of forty patients with acute AlP poisoning admitted to TUPCC in the period from the 1st of March 2019 to the 1st of March 2020. Only patients with AlP poisoning were included in the current study. Patients with alleged zinc phosphide ingestion who were admitted to TUPCC during the study did not match the inclusion criteria.