الفهرس 
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Abstract
Infertility is defined by the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse.
The lack of ovulatory cycles may be considered as a major problem for women seeking pregnancy. This is reflected by the fact that about 20 percent of couples visiting a fertility clinic with an unfulfilled wish to conceive present with anovulation (Barthelmess and Naz, 2014).
Ovulation induction involves taking medication to induce ovulation by encouraging eggs to develop in the ovaries and be released, increasing the chance of conception through timed intercourse
Triggering of ovulation means taking medication to promote follicular rupture and release of ovum
Several studies have explained the effect of many protocols on the ovulation and conception rates in ovulatory infertile women and hormone (LH) surge and maturation of the final stage of oocyte in these patients (Raju et al., 2013).
Human chorionic gonadotropin (HCG) is the most common protocol that has been used in combination with clomiphene citrate in these women as an alteration to L.H for a long time. This method has been used as the standard approach for the induction of final stages of oocyte maturation (Yilmaz et al., 20016).
HCG was selected due to its luteinizing hormone like effect while isolated or purified human L.H could not be obtained (Riccetti et al., 2017).
Although similar in structure and function and there is a difference in pharmacokinetics and bioavailability between HCG and LH that may lead to high risk of ovarian hyperstimulation (OHSS) after administration of HCG due to sustained luiteotropic effect of HCG (Casarini et al. 2012).
There is a lot of treatment methods have been developed over the years to find a suitable alternative for HCG as using low dose gonadotropin releasing hormone agonist; but it is not commonly used probably due to cost factor (Kol and Fainaru, 2017).
One of the regimens that being explored is using oxytocin to trigger ovulation as they are found in some trials (Mehrotra et al., 2014).
Oxytocin is a neuropeptide hormone produced in the hypothalamic-neurohypophyseal system and has a well-established role in labour and lactation. Recently, some reports found oxytocin in gonads of different species including man (Hashimoto et al., 2012).
Oxytocin has been found to be locally produced in the ovary. It is produced by granulosa cells (GCs) of pre-ovulatory ovarian follicles and the corpus luteum (CL) in some mammalian species. Actions of oxytocin in the ovary have been linked to luteinization, steroidogenesis and luteolysis (Saller et al., 2010).
In our study, we evaluated the efficacy of oxytocin as a triggering of ovulation in comparison to human chorionic gonatotropin in patients undergoing induction of ovulation.
In the present study, there was no statistically significant difference between groups in regards baseline characteristics like (age, BMI, type of infertility) and hormonal profile.
In our study, there was a statistically significant difference between groups in terms of number of ruptured follicles 48 hours after trigger. Patients who received HCG had significantly higher number of ruptured follicles than oxytocin group.