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Abstract Purpose: To investigate the potential application of new MRI techniques with emphasis to diffusion weighted echo planar imaging (DW-EPI) in characterization and differentiation between various entities of salivary gland tumors and to correlate diffusion patterns & ADC values of different salivary lesions with their pathological nature. Material and Methods: from August 2017 and May 2019 twenty one patients presented with salivary gland swelling (11 benign and 10 malignant) were assessed by MR images, (DWI). Diffusion was done by SE-EPI sequence using b values from 0 to 1000. The ADC value was then automatically calculated. Results: The mean ADC value of the normal salivary glands was found to be 0.962 ± 0.078 x 10-3mm2/s. The mean ADC value for benign tumors was 1.29 ± 0.26 x 10-3mm2/s, while the mean ADC value of malignant tumors found to be 0.72 ± 0.19 x 10-3mm2/s. However, overlap still exists. ROC analysis produced cut off values of 0.89 x 10-3 mm2/sec between benign and malignant lesions with sensitivity 90% and specificity 90.9%. Conclusion: To Determine whether the salivary gland tumor is benign or malignant on the basis of combining morphologic features and DWIs & ADC measurements in a diagnostic noninvasive approach are very promising and might decrease number of unnecessary invasive procedures e.g. biopsies or inappropriate extensive surgical approaches for benign salivary gland lesions. |