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العنوان
The Role of Diffusion-Weighted MRI in Differentiation between Salivary Gland Tumors /
الناشر
Ain Shames University.
المؤلف
Hamed,Hassan Ramadan .
هيئة الاعداد
باحث / حسن رمضان حامد
مشرف / راندا حسين عبد الله
مشرف / ريمــون زاهـــر إيليــا
مشرف / أمــل إبراهيـم أحمـد
تاريخ النشر
2021
عدد الصفحات
168.p;
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
1/1/2021
مكان الإجازة
جامعة عين شمس - كلية الطب - Radio diagnosis
الفهرس
Only 14 pages are availabe for public view

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from 163

Abstract

Purpose: To investigate the potential application of new MRI techniques with emphasis to diffusion weighted echo planar imaging (DW-EPI) in characterization and differentiation between various entities of salivary gland tumors and to correlate diffusion patterns & ADC values of different salivary lesions with their pathological nature.
Material and Methods: from August 2017 and May 2019 twenty one patients presented with salivary gland swelling (11 benign and 10 malignant) were assessed by MR images, (DWI). Diffusion was done by SE-EPI sequence using b values from 0 to 1000. The ADC value was then automatically calculated.
Results: The mean ADC value of the normal salivary glands was found to be 0.962 ± 0.078 x 10-3mm2/s. The mean ADC value for benign tumors was 1.29 ± 0.26 x 10-3mm2/s, while the mean ADC value of malignant tumors found to be 0.72 ± 0.19 x 10-3mm2/s. However, overlap still exists. ROC analysis produced cut off values of 0.89 x 10-3 mm2/sec between benign and malignant lesions with sensitivity 90% and specificity 90.9%.
Conclusion: To Determine whether the salivary gland tumor is benign or malignant on the basis of combining morphologic features and DWIs & ADC measurements in a diagnostic noninvasive approach are very promising and might decrease number of unnecessary invasive procedures e.g. biopsies or inappropriate extensive surgical approaches for benign salivary gland lesions.