الفهرس 
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Abstract
This study was carried out in a broiler farm under the supervision of Animal Production Department, Faculty of Agriculture, Tanta University during the period from March to May 2016 to investigate the effects of supplementation of different sources of selenium ( inorganic; sodium selenite, organic; selenium yeast or nano) on growth performance, blood biochemical profiles and immune response of broiler chicks. Two hundred and forty oneday- old unsexed Cobb broilers chicks were used in this experiment. Birds were wing-banded, individually weighed to the nearest gram, and randomly distributed into four equal experimental groups; with three replicates of 20 chicks each. The average initial body weights of the treatment groups were nearly similar with no observed significant differences. The chicks were offered two corn-soybean meal basal mash diets that were formulated to meet or exceed the Nutritional Requirement of growing chicks as recommended by the National Research Council (NRC). The experimental designed was included: Control Basal diet without any addition T1 (0.4 InSe) Basal diet plus 0.4 mg/kg inorganic selenium (sodium selenite ) T2 (0.4 OrSe) Basal diet plus 0.4 mg/kg organic selenium (selenium yeast ) T3 (0.2 NaSe) Basal diet plus 0.2 mg/kg nano selenium All birds were subjected to the same managerial, hygienic and environmental conditions. The birds were grown in floor litter condition and subjected to 24 hrs, which extended to 5 weeks of age. The house temperature was kept at about 34ºC during the first 3 days, 32ºC during next 4 days and thereafter, Summary and Conclusion 85 gradually decreased by 2-3ºC weekly down to 22-24ºC. Mash feed form and water were available ad labium throughout the experimental period. Individual live body weight and feed intake were recorded weekly during the experiment. Weight gain and feed conversion ratio were calculated on a group. At the end of the feeding trial, all birds were fasted for 12 hrs prior to final sampling. Three birds from each replicate were randomly selected weighed, slaughtered by slitting the jugular vein of the birds in the morning, then after slaughter and complete bleeding scalded and defeathered. Carcasses chicks were eviscerated manually and weighed. Liver, spleen, burse, heart and thymus were removed carefully and weighed. All organs weights were expressed as percentage of body weight and subjected to arcsine transformation. Three blood samples were collected from three birds in each group during slaughtering, one with EDTA while the other without; tubes in EDTA-containing for determination of the biochemical parameters.. Chicks of plasma or serum were obtained immediately by centrifugation the blood for 10 min. at 3000 rpm and frozen rapidly in ependorf tubes until the time of analysis. Total protein, liver function enzymes, lipid profile and antioxidant status were measured. The results indicated that:- 1- Broilers in all treatments, which were dieted with inorganic, organic or nano selenium had a significant effect on body weight as comparing to control group. The highest value was in the birds fed on organic selenium, then the birds fed on Nano selenium compared to control ones. 2- There are a significant effect of selenium on feed consumption and feed conversion ratio. Birds fed organic selenium had the best value the nano selenium birds followed by inorganic group. Summary and Conclusion 06 3- Broilers dietary with selenium (organic, inorganic or nano forms) had no significant effect on mortality rate as compared with the control. 4- There is had no significant effect of broilers diet with selenium on carcass percentage, spleen and heart. On the other hand there is a significant effect of broiler diet with selenium on liver, bursa and thymus weight (%). 5- Selenium had no significant effect on the concentration of AST and ALT. On the other hand selenium in the birds diet led to an enhancement in values of total protein,globulin, albumin, HDL , LDL, total lipids, triglyceride, total cholesterol, total antioxidant capacity, MDA and SOD. Conclusion, it could be recommended that supplementation of selenium sources in broiler diets could improve productive performance, antioxidant status and physiological response in broiler chicks through 35 days of age.